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Article
Article
A chimeric RNA consisting of siRNA and aptamer for inhibiting dengue virus replication
A chimeric RNA consisting of siRNA and aptamer for inhibiting dengue virus replication
Ryo Amano, Masaki Takahashi*, Kazumi Haga, Mizuki Yamamoto, Kaku Goto, Akiko Ichinose, Michiaki Hamada, Jin Gohda, Jun-ichiro Inoue, Yasushi Kawaguchi, Meng Ling Moi, Yoshikazu Nakamura
Nucleic Acids Research Molecular Medicine
December 2024
Article
Article
Structural and molecular properties of mumps virus inclusion bodies
Structural and molecular properties of mumps virus inclusion bodies
Hiroshi Katoh, Ryuichi Kimura, Tsuyoshi Sekizuka, Kohei Matsuoka, Mika Hosogi, Yuki Kitai, Yukiko Akahori, Fumihiro Kato, Michiyo Kataoka, Hirotaka Kobayashi, Noriyo Nagata, Tadaki Suzuki, Yasuyuki Ohkawa, Shinya Oki, Makoto Takeda
December 2024
News
News
In the south-western Democratic Republic of Congo (DRC), a mysterious flu-like illness has reportedly caused the deaths of over 79 people. More than 300 cases have been reported, with symptoms including fever, headaches, coughing, breathing difficulties, and anemia.
9 December 2024 (updated on 19 December 2024 and 6 January 2025) Event
Event
UTOPIA welcomed researchers from the Kenya Medical Research Institute (KEMRI)
UTOPIA welcomed researchers from the Kenya Medical Research Institute (KEMRI)
29 November 2024
News
News
Three members from UTOPIA have been selected for a research grant from the Takeda Science Foundation. Congratulations!
High-Risk Emerging Infectious Diseases Research Grant
High-Risk Emerging Infectious Diseases Research Grant
Ryuta Uraki (UTOPIA)
Medical Research Grant
Medical Research Grant
Shiro Chiba (UTOPIA)
Visionary Research Grant (Start)
Visionary Research Grant (Start)
Naoki Morita (Institute for Quantitative Bioscience)
Article
Article
Virological characteristics of the SARS-CoV-2 XEC variant
Virological characteristics of the SARS-CoV-2 XEC variant
Kaku Y, Okumura K, Kawakubo S, Uriu K, Chen L, Kosugi Y, Uwamino Y, Begum MM, Leong S, Ikeda Sadamasu K, Asakura H, Nagashima M, Yoshimura K, Ito J, Sato K,
The Lancet Infectious Diseases
November 2024
Article
Article
Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1.
Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1.
Yajima H, Anraku Y, Kaku Y, Kimura KT, Plianchaisuk A, Okumura K, Nakada-Nakura Y, Atarashi Y, Hemmi T, Kuroda D, Takahashi Y, Kita S, Sasaki J, Sumita H; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ito J, Maenaka K, Sato K, Hashiguchi T.
October 2024
Article
Article
Shiho Chiba*, Maki Kiso, Shinya Yamada, Kazuhiko Someya, Yoshikuni Onodera, Aya Yamaguchi, Satoko Matsunaga, Nao Jounai, Seiya Yamayoshi, Fumihiko Takeshita, and Yoshihiro Kawaoka¶
October 2024
Video
Video
Professor Yasuhiro Yamada
Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo
Professor Yasuhiro Yamada
Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo
October 2024
October 2024
Event
Event
UTOPIA welcomed a delegation from the University of New South Wales.
UTOPIA welcomed a delegation from the University of New South Wales.
From left: Professor Colin Grant, Professor Yoshihiro Kawaoka, Professor Dane McCamey and Dr Ian Langford
30 October 2024
Article
Article
A human isolate of bovine H5N1 is transmissible and lethal in animal models
A human isolate of bovine H5N1 is transmissible and lethal in animal models
Chunyang Gu*, Tadashi Maemura*, Lizheng Guan*, Amie J. Eisfeld*, Asim Biswas*, Maki Kiso*, Ryuta Uraki, Mutsumi Ito, Sanja Trifkovic, Tong Wang, Lavanya Babujee, Robert Presler Jr., Randall Dahn, Yasuo Suzuki, Peter J. Halfmann, Seiya Yamayoshi, Gabriele Neumann, and Yoshihiro Kawaoka
News Release
H5N1 virus isolated from infected dairy worker is 100% lethal in ferrets, but does not appear to be circulating in nature anymore
October 2024
Event
Event
World Flu Day 2024 Symposium /
9th Japan-China Bilateral Symposium on All Influenza Viruses (WFD-JCS 2024)
Supported by The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA)
World Flu Day 2024 Symposium /
9th Japan-China Bilateral Symposium on All Influenza Viruses (WFD-JCS 2024)
Supported by The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA)
1 - 2 November 2024 | Shirokanedai, Tokyo
Video
Video
Professor Taisuke Horimoto
Department of Veterinary Microbiology, the University of Tokyo
Professor Taisuke Horimoto
Department of Veterinary Microbiology, the University of Tokyo
October 2024
October 2024
Article
Article
Low-frequency CD8+ T cells induced by SIGN-R1+ macrophage-targeted vaccine confer SARS-CoV-2 clearance in mice
Low-frequency CD8+ T cells induced by SIGN-R1+ macrophage-targeted vaccine confer SARS-CoV-2 clearance in mice
Muraoka D, Moi ML, Muto O, Nakatsukasa T, Deng S, Takashima C, Yamaguchi R, Sawada SI, Hayakawa H, Nguyen TTN, Haseda Y, Soga T, Matsushita H, Ikeda H, Akiyoshi K, Harada N.
October 2024
Video
Video
UTOPIA 43 Interviews | Vol. 27
Toll-like Receptors: Host Defense, Inflammation, and Autoimmune Diseases
UTOPIA 43 Interviews | Vol. 27
Toll-like Receptors: Host Defense, Inflammation, and Autoimmune Diseases
Professor Kensuke Miyake
Professor Kensuke Miyake
Division of Infectious Genetics, Institute of Medical Science, University of Tokyo
Division of Infectious Genetics, Institute of Medical Science, University of Tokyo
September 2024
September 2024
Video
Video
UTOPIA 43 Interviews | Vol. 26
From Treating Patients to Discovering Cures: A Path into Stem Cell Research
UTOPIA 43 Interviews | Vol. 26
From Treating Patients to Discovering Cures: A Path into Stem Cell Research
Professor Atsushi Iwama
Professor Atsushi Iwama
Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, Institute of Medical Science, The University of Tokyo
September 2024
September 2024
Event
Event
13 September 2024 | Auditorium, IMSUT
14:00 - 15:00
Dr. Masaru Kanekiyo
Vaccine and antibody discovery targeting influenza virus neuraminidase
14:00 - 15:00
Dr. Masaru Kanekiyo
Vaccine and antibody discovery targeting influenza virus neuraminidase
Organizers: Koji Kobiyama, Cevayir Coban
Article
Article
Review Article
BCR signaling in germinal center B cell selection
BCR signaling in germinal center B cell selection
Takeshi Inoue, Yoshihiro Baba, Tomohiro Kurosaki
→Share Link (Free Access until 9 Oct 2024)
August 2024
Article
Article
Virological characteristics of the SARS-CoV-2 KP.3.1.1 variant
Virological characteristics of the SARS-CoV-2 KP.3.1.1 variant
Kaku Y, Uriu K, Okumura K; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ito J, Sato K.
The Lancet Infectious Diseases Relevant posts on X
August 2024
News
News
For UTokyo Members Only (Science and Humanities)
For UTokyo Members Only (Science and Humanities)
The 2024 UTOPIA
AI Research Discovery Program
The 2024 UTOPIA
AI Research Discovery Program
<Deadline: 15:00, Thursday, 22 August 2024>
<Deadline: 15:00, Thursday, 22 August 2024>
August 2024
August 2024
Event
Event
20 August 2024 | Auditorium, IMSUT
16:30 - 17:15
Dr. Sebastian Hofer
EIF5A and Polyamines are required for fasting-mediated autophagy and longevity
16:30 - 17:15
Dr. Sebastian Hofer
EIF5A and Polyamines are required for fasting-mediated autophagy and longevity
17:15 - 18:00
Dr. Ghada Alsaleh
Autophagy as a pathway to rejuvenate immune responses
17:15 - 18:00
Dr. Ghada Alsaleh
Autophagy as a pathway to rejuvenate immune responses
Organizer Professor Cevayir Coban
Organizer Professor Cevayir Coban
Video
Video
UTOPIA 43 Interviews | Vol. 25
Making a Difference: Fighting Infections from Molecular to Global Level
UTOPIA 43 Interviews | Vol. 25
Making a Difference: Fighting Infections from Molecular to Global Level
Professor Yuki Furuse
Department of Microbiology and Infection; The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA)
Professor Yuki Furuse
Department of Microbiology and Infection; The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA)
July 2024
July 2024
News
News
For UTokyo Members Only (Science and Humanities)
The 2024 UTOPIA Young Researcher Development Program <Deadline: 15:00, Thursday, 8 August 2024>
For UTokyo Members Only (Science and Humanities)
The 2024 UTOPIA Young Researcher Development Program <Deadline: 15:00, Thursday, 8 August 2024>
July 2024
July 2024
Event
Event
World Flu Day 2024 Symposium /
9th Japan-China Bilateral Symposium on All Influenza Viruses (WFD-JCS 2024)
Supported by The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center
World Flu Day 2024 Symposium /
9th Japan-China Bilateral Symposium on All Influenza Viruses (WFD-JCS 2024)
Supported by The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center
1 - 2 November 2024 | Shirokanedai, Tokyo
Video
Video
Professor Takeshi Inoue
Department of Molecular Systems Immunology; The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA)
Professor Takeshi Inoue
Department of Molecular Systems Immunology; The University of Tokyo Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA)
July 2024
Article
Article
Pathogenicity and transmissibility of bovine H5N1 influenza virus
Pathogenicity and transmissibility of bovine H5N1 influenza virus
Eisfeld AJ, Biswas A, Guan L, Gu C, Maemura T, Trifkovic S, Wang T, Babujee L, Dahn R, Halfmann PJ, Barnhardt T, Neumann G, Suzuki Y, Thompson A, Swinford AK, Dimitrov KM, Poulsen K, Kawaoka Y.
News Release
Raw milk is risky, but airborne transmission of H5N1 from cow's milk is inefficient in mammals
Jully 2024
Related Conference
Related Conference
The ISV Annual Congress will be held in Seoul, for which Prof. Ken Ishii will serve as one of the Congress Chairs.
The ISV Annual Congress will be held in Seoul, for which Prof. Ken Ishii will serve as one of the Congress Chairs.
Event
Event
The Second UTOPIA Symposium was held from June 19 to 20 in Fuchu.
The Second UTOPIA Symposium was held from June 19 to 20 in Fuchu.
Click here for photos and details about Flash Talk Awards and Poster Awards.
Event
Event
UTOPIA Seminar
UTOPIA Seminar
Topic: Combatting tuberculosis and publishing in medical journals
Topic: Combatting tuberculosis and publishing in medical journals
Speaker: ERIC J. RUBIN, MD, PHD
Editor-in-Chief, The New England Journal of Medicine, NEJM Group
Speaker: ERIC J. RUBIN, MD, PHD
Editor-in-Chief, The New England Journal of Medicine, NEJM Group
Date/Time: Friday, 12 July 2024, 16:00 – 17:00 (JST)
Place: Auditorium, 1st building, The Institute of Medical Science, The University of Tokyo
June 2024
Event
Event
Innate lymphoid cells: development, differentiation, dynamics
Innate lymphoid cells: development, differentiation, dynamics
Professor James Di Santo, MD, PhD
Institut Pasteur
Professor James Di Santo, MD, PhD
Institut Pasteur
AM 10:00 - 11:30, Friday, 21 June 2024
Auditorium, Institute of Medical Science, The University of Tokyo
Article
Article
Cow’s Milk Containing Avian Influenza A(H5N1) Virus — Heat Inactivation and Infectivity in Mice
Cow’s Milk Containing Avian Influenza A(H5N1) Virus — Heat Inactivation and Infectivity in Mice
Guan L, Eisfeld AJ, Pattinson D, Gu C, Biswas A, Maemura T, Trifkovic S, Babujee L, Presler R Jr, Dahn R, Halfmann PJ, Barnhardt T, Neumann G, Thompson A, Swinford AK, Dimitrov KM, Poulsen K, Kawaoka Y.
New England Journal of Medicine
May 2024
Article
Article
Memory CD8 T cells are vulnerable to chronic IFN-γ signals but not to CD4 T cell deficiency in MHCII-deficient mice
Memory CD8 T cells are vulnerable to chronic IFN-γ signals but not to CD4 T cell deficiency in MHCII-deficient mice
Setoguchi R, Sengiku T, Kono H, Kawakami E, Kubo M, Yamamoto T, Hori S
May 2024
Article
Article
Inoue T, Matsumoto Y, Kawai C, Ito M, Nada S, Okada M, Kurosaki T
Journal of Experimental Medicine
May 2024
Video
Video
Professor Makoto Takeda
Department of Microbiology, Graduate School of Medicine, The University of Tokyo
Professor Makoto Takeda
Department of Microbiology, Graduate School of Medicine, The University of Tokyo
May 2024
Video
Video
Professor Takao Someya
Department of Electrical Engineering and Information Systems, Graduate School of Engineering, The University of Tokyo
May 2024
Video
Video
Professor Tomoki Todo
Hospital Director, The Institute of Medical Science, The University of Tokyo
Professor Tomoki Todo
Hospital Director, The Institute of Medical Science, The University of Tokyo
April 2024
Video
Video
Professor Toshifumi Inada
Division of RNA and Gene Regulation
The Institute of Medical Science, The University of Tokyo
Professor Toshifumi Inada
Division of RNA and Gene Regulation
The Institute of Medical Science, The University of Tokyo
April 2024
Event
Event
UTOPIA Welcomes Representatives from HHS/ASPR, CDC, US Embassy, and Japan's Ministry of Health, Labour and Welfare
UTOPIA Welcomes Representatives from HHS/ASPR, CDC, US Embassy, and Japan's Ministry of Health, Labour and Welfare
18 March 2024
Video
Video
Takeshi Ichinohe, Associate Professor
Division of Viral Infection, Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo
Takeshi Ichinohe, Associate Professor
Division of Viral Infection, Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo
March 2024
Video
Video
Takashi Okada, Professor
Director, Center for Gene and Cell Therapy, The Institute of Medical Science, The University of Tokyo
Takashi Okada, Professor
Director, Center for Gene and Cell Therapy, The Institute of Medical Science, The University of Tokyo
March 2024
Article
Article
TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA
TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA
Nakamura T, Ohyama C, Sakamoto M, Toma T, Tateishi H, Matsuo M, Chirifu M, Ikemizu S, Morioka H, Fujita M, Inoue J, Yamagata Y
Proceedings of the National Academy of Sciences of the United States of America
March 2024
Video
Video
UTOPIA 43 Interviews | Vol. 17
Malaria Research Beyond Borders: Protecting People around the Globe
UTOPIA 43 Interviews | Vol. 17
Malaria Research Beyond Borders: Protecting People around the Globe
Cevayir Coban, Professor
Division of Malaria Immunology, The Institute of Medical Science, The University of Tokyo
Cevayir Coban, Professor
Division of Malaria Immunology, The Institute of Medical Science, The University of Tokyo
February 2024
Article
Article
Age-associated CD4+ T cells with B cell-promoting functions are regulated by ZEB2 in autoimmunity
Age-associated CD4+ T cells with B cell-promoting functions are regulated by ZEB2 in autoimmunity
Goto M, Takahashi H, Yoshida R, Itamiya T, Nakano M, Nagafuchi Y, Harada H, Shimizu T, Maeda M, Kubota A, Toda T, Hatano H, Sugimori Y, Kawahata K, Yamamoto K, Shoda H, Ishigaki K, Ota M, Okamura T, Fujio K.
February 2024
Video
Video
Journalist Meets Scientist - Protect People from Infectious Diseases (UTOPIA Special Interview)
Journalist Meets Scientist - Protect People from Infectious Diseases (UTOPIA Special Interview)
Takako Zenba, the host of TBS's 'Houdou Tokushu' , meets Professor Yoshihiro Kawaoka, a virologist and the Director of The UTOPIA Center
Takako Zenba, the host of TBS's 'Houdou Tokushu' , meets Professor Yoshihiro Kawaoka, a virologist and the Director of The UTOPIA Center
February 2024
News
News
PLATINUM STREET TIMES Vol. 7
PLATINUM STREET TIMES Vol. 7
The dialogue between Takako Zenba and Professor Yoshihiro Kawaoka, Director of UTOPIA, has been featured in the magazine "PLATINUM STREET TIMES Vol. 7 (December 2023)," published by the Institute of Medical Science, the University of Tokyo (in Japanese). Please refer to pages 8-9.
The dialogue can also be watched on YouTube.
The dialogue between Takako Zenba and Professor Yoshihiro Kawaoka, Director of UTOPIA, has been featured in the magazine "PLATINUM STREET TIMES Vol. 7 (December 2023)," published by the Institute of Medical Science, the University of Tokyo (in Japanese). Please refer to pages 8-9.
The dialogue can also be watched on YouTube.
February 2024
Event
Event
The First Joint Symposium of AMED SCARDA Japan Initiative for World-leading Vaccine Research and Development Centers was held from January 31st to February 2nd in Kyoto.
The First Joint Symposium of AMED SCARDA Japan Initiative for World-leading Vaccine Research and Development Centers was held from January 31st to February 2nd in Kyoto.
February 2024
Video
Video
UTOPIA 43 Interviews | Vol. 16
Nurturing Research Discoveries into Real-world Applications to Save Lives
UTOPIA 43 Interviews | Vol. 16
Nurturing Research Discoveries into Real-world Applications to Save Lives
Fumitaka Nagamura, Professor
Center for Translational Research/Division of Advanced Medicine Promotion, The Advanced Clinical Center, The Institute of Medical Science, The University of Tokyo
Fumitaka Nagamura, Professor
Center for Translational Research/Division of Advanced Medicine Promotion, The Advanced Clinical Center, The Institute of Medical Science, The University of Tokyo
January 2024
Event
Event
Visit by GLEAP: Students from the Seoul National University's College of Natural Sciences
Visit by GLEAP: Students from the Seoul National University's College of Natural Sciences
Date and Time: 10 January 2024, 9:30 - 11:30
January 2024
Event
Event
UTOPIA Seminar
UTOPIA Seminar
Topic: Antibody responses to SARS-CoV-2 infection and vaccination
Topic: Antibody responses to SARS-CoV-2 infection and vaccination
Speaker: Florian Krammer, Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
Speaker: Florian Krammer, Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
Date/Time: Thursday, 18 January 2024 16:00 -
Place: Auditorium, 1st building, The Institute of Medical Science, The University of Tokyo
January 2024
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